Protein basic information
| LiverAtlas Protein ID |
HuLPr47531 |
|
Uniprot ID |
|
|
Uniprot Acc |
O60296;Q8WVH7;Q96NS2;Q9C0K5;Q9C0K6; |
|
Protein name |
Trafficking kinesin-binding protein 2 |
|
Comment |
FUNCTION:May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity).||SUBUNIT:Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.||SUBCELLULAR LOCATION:Cytoplasm (By similarity). Early endosome (By similarity).||TISSUE SPECIFICITY:Widely expressed, with highest expression in heart.||PTM:O-glycosylated (By similarity).||SIMILARITY:Contains 1 HAP1 N-terminal domain. |
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Subcellular localization |
Cytoplasm(By similarity).Early endosome(By similarity). |
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Gene name |
|
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Protein sequence
|
MSQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPE VELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHA SDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHL LAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQA FDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLR FNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIK TETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKS DELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQ ASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRS RSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEE SSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGS NRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQ KMGQPGPSGDSDLATALHRLSLRRQNYLSEKQFFAEEWQ RKIQVLADQKEGVSGCVTPTESLASLCTTQSEITDLSSA SCLRGFMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILD PRPGVITKGFTQLPGDAIYHISDLEEDEEEGITFQVQQP LEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANPGKCL SCTNSTFTFTTCRILHPSDITQVTPSSGFPSLSCGSSGS SSSNTAVNSPALSYRLSIGESITNRRDSTTTFSSTMSLA KLLQERGISAKVYHSPISENPLQPLPKSLAIPSTPPNSP SHSPCPSPLPFEPRVHLSENFLASRPAETFLQEMYGLRP SRNPPDVGQLKMNLVDRLKRLGIARVVKNPGAQENGRCQ EAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAPVCTSSPKMGVLKED |
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Database cross reference |
RefSeq Protein accession:NP_055864
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005769;C:early endosome;IEA:UniProtKB-SubCell. GO:0005886;C:plasma membrane;ISS:UniProtKB. |
|
GO-F |
GO:0050811;F:GABA receptor binding;NAS:HGNC. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr47531 |
PHOSPHORYLATION |
776 |
T |
PhosphoSitePlus |
LTP |
N |
 
|
|
|
HuLPr47531 |
PHOSPHORYLATION |
280 |
Y |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr47531 |
PHOSPHORYLATION |
285 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr47531 |
ACETYLATION |
299 |
K |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr47531 |
PHOSPHORYLATION |
780 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr47531 |
PHOSPHORYLATION |
784 |
S |
PhosphoSitePlus |
HTP |
N |
|
