HuLPr47833

Uniprot ID

TUT7_HUMAN

Uniprot Acc

Q5VYS8;Q5H9T0;Q5VYS5;Q5VYS7;Q658Z9;Q659A2;Q6MZJ3;Q8N5F0;Q96N57;Q96NE8;Q9C0F2;Q9H8M6;

Protein name

Terminal uridylyltransferase 7

Comment

FUNCTION:Uridylyltransferase that mediates the terminal uridylation of some specific RNAs. Not involved in uridylation of precursor let-7 (pre-let-7) miRNA. Does not play a role in replication-dependent histone mRNA degradation.||CATALYTIC ACTIVITY:UTP + RNA(n) = diphosphate + RNA(n+1).||COFACTOR:Magnesium or manganese (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=6; Name=1; IsoId=Q5VYS8-1; Sequence=Displayed; Name=2; IsoId=Q5VYS8-2; Sequence=VSP 013837, VSP 013838; Note=No experimental confirmation available; Name=3; IsoId=Q5VYS8-3; Sequence=VSP 013835, VSP 013836; Note=No experimental confirmation available; Name=4; IsoId=Q5VYS8-4; Sequence=VSP 013832, VSP 013839; Note=No experimental confirmation available; Name=5; IsoId=Q5VYS8-5; Sequence=VSP 013833, VSP 013834; Note=No experimental confirmation available; Name=6; IsoId=Q5VYS8-6; Sequence=VSP 013840; Note=No experimental confirmation available;||SIMILARITY:Belongs to the DNA

Gene name

zinc finger, CCHC domain containing 6

Protein sequence

MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHA KGHGSKMEKGLQKKKITPGNYGNTPRKGPCAVSSNPYAF KNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKP GPRIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHK DLTSLETTSEMEAGSPENKKQRSRPRKPRKTRNEENEQD GDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRR PRNYPTAKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKE KQEEELLTTLPPPTPSQINAVGIAIDKVVQEFGLHNENL EQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSD VNIDIQFPAIMSQPDVLLLVQECLKNSDSFIDVDADFHA RVPVVVCREKQSGLLCKVSAGNENACLTTKHLTALGKLE PKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFF LQQRKEPLLPVYLGSWIEGFSLSKLGNFNLQDIEKDVVI WEHTDSAAGDTGITKEEAPRETPIKRGQVSLILDVKHQP SVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELK DWPKKRIAIEDPYSVKRNVARTLNSQPVFEYILHCLRTT YKYFALPHKITKSSLLKPLNAITCISEHSKEVINHHPDV QTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAES FGSPPKEEMGNEHISVHPENSDCIQADVNSDDYKGDKVY HPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGT EELEDSLNHFTHSVQGQTSEMIPSDEEEEDDEEEEEEEE PRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDE LGEAAKYEDVKECGKHVERALLVELNKISLKEENVCEEK NSPVDQSDFFYEFSKLIFTKGKSPTVVCSLCKREGHLKK DCPEDFKRIQLEPLPPLTPKFLNI

Database cross reference

RefSeq Protein accession:NP_001171988
RefSeq Protein gi:297307111

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

GO-F

GO:0003676;F:nucleic acid binding;IEA:InterPro. GO:0050265;F:RNA uridylyltransferase activity;IDA:UniProtKB. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0031123;P:RNA 3'-end processing;IDA:UniProtKB.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr47833

PHOSPHORYLATION

172

S

Phospho-ELM

41449

HTP

N

HuLPr47833

PHOSPHORYLATION

57

T

Phospho-ELM

41453

HTP

N

HuLPr47833

PHOSPHORYLATION

599

Y

Phospho-ELM

41455

HTP

N

HuLPr47833

PHOSPHORYLATION

600

S

Phospho-ELM

41450

HTP

N

HuLPr47833

PHOSPHORYLATION

64

T

Phospho-ELM

41454

HTP

N

HuLPr47833

PHOSPHORYLATION

844

S

Phospho-ELM

41451

HTP

N

HuLPr47833

PHOSPHORYLATION

939

S

Phospho-ELM

41452

HTP

N

HuLPr47833

PHOSPHORYLATION

172

S

PhosphoSitePlus

3201945

LTP

N

HuLPr47833

PHOSPHORYLATION

844

S

PhosphoSitePlus

3201951

HTP

N

HuLPr47833

PHOSPHORYLATION

939

S

PhosphoSitePlus

3201954

LTP

N

HuLPr47833

PHOSPHORYLATION

57

T

PhosphoSitePlus

3201957

LTP

N

HuLPr47833

PHOSPHORYLATION

64

T

PhosphoSitePlus

3201960

LTP

N

HuLPr47833

PHOSPHORYLATION

1297

T

PhosphoSitePlus

17551738

LTP

N

HuLPr47833

PHOSPHORYLATION

33

Y

PhosphoSitePlus

476874

LTP

N

HuLPr47833

PHOSPHORYLATION

132

S

PhosphoSitePlus

477934

LTP

HTP

N