HuLPr47996

Uniprot ID

UBP31_HUMAN

Uniprot Acc

Q70CQ4;Q6AW97;Q6ZTC0;Q6ZTN2;Q9ULL7;

Protein name

Ubiquitin carboxyl-terminal hydrolase 31

Comment

FUNCTION:May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquinated proteins (By similarity).||CATALYTIC ACTIVITY:Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C- terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q70CQ4-1; Sequence=Displayed; Name=2; IsoId=Q70CQ4-2; Sequence=VSP 020459, VSP 020460, VSP 020461, VSP 020462; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Widely expressed.||SIMILARITY:Belongs to the peptidase C19 family.||SEQUENCE CAUTION:Sequence=AK126752; Type=Frameshift; Positions=941;

Gene name

ubiquitin specific peptidase 31

Protein sequence

MSKVTAPGSGPPAAASGKEKRSFSKRLFRSGRAGGGGAGG PGASGPAAPSSPSSPSSARSVGSFMSRVLKTLSTLSHLS SEGAAPDRGGLRSCFPPGPAAAPTPPPCPPPPASPAPPA CAAEPVPGVAGLRNHGNTCFMNATLQCLSNTELFAEYLA LGQYRAGRPEPSPDPEQPAGRGAQGQGEVTEQLAHLVRA LWTLEYTPQHSRDFKTIVSKNALQYRGNSQHDAQEFLLW LLDRVHEDLNHSVKQSGQPPLKPPSETDMMPEGPSFPVC STFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIP LPHTRPLYVTVVYQGKCSHCMRIGVAVPLSGTVARLREA VSMETKIPTDQIVLTEMYYDGFHRSFCDTDDLETVHESD CIFAFETPEIFRPEGILSQRGIHLNNNLNHLKFGLDYHR LSSPTQTAAKQGKMDSPTSRAGSDKIVLLVCNRACTGQQ GKRFGLPFVLHLEKTIAWDLLQKEILEKMKYFLRPTVCI QVCPFSLRVVSVVGITYLLPQEEQPLCHPIVERALKSCG PGGTAHVKLVVEWDKETRDFLFVNTEDEYIPDAESVRLQ RERHHQPQTCTLSQCFQLYTKEERLAPDDAWRCPHCKQL QQGSITLSLWTLPDVLIIHLKRFRQEGDRRMKLQNMVKF PLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPE DYIYDLYAVCNHHGTMQGGHYTAYCKNSVDGLWYCFDDS DVQQLSEDEVCTQTAYILFYQRRTAIPSWSANSSVAGST SSSLCEHWVSRLPGSKPASVTSAASSRRTSLASLSESVE MTGERSEDDGGFSTRPFVRSVQRQSLSSRSSVTSPLAVN ENCMRPSWSLSAKLQMRSNSPSRFSGDSPIHSSASTLEK IGEAADDKVSISCFGSLRNLSSSYQEPSDSHSRREHKAV GRAPLAVMEGVFKDESDTRRLNSSVVDTQSKHSAQGDRL PPLSGPFDNNNQIAYVDQSDSVDS

Database cross reference

RefSeq Protein accession:NP_065769
RefSeq Protein gi:120587027

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

GO-F

GO:0008234;F:cysteine-type peptidase activity;IEA:UniProtKB-KW. GO:0004221;F:ubiquitin thiolesterase activity;IEA:InterPro.

GO-P

GO:0006511;P:ubiquitin-dependent protein catabolic process;IEA:InterPro.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr47996

PHOSPHORYLATION

1052

S

Phospho-ELM

21925

HTP

N

HuLPr47996

PHOSPHORYLATION

1056

T

Phospho-ELM

21926

HTP

N

HuLPr47996

PHOSPHORYLATION

428

Y

PhosphoSitePlus

2470219

LTP

N

HuLPr47996

PHOSPHORYLATION

398

T

PhosphoSitePlus

13310280

LTP

N

HuLPr47996

PHOSPHORYLATION

1022

T

PhosphoSitePlus

485144

LTP

HTP

N

HuLPr47996

PHOSPHORYLATION

1023

T

PhosphoSitePlus

485145

LTP

N

HuLPr47996

PHOSPHORYLATION

1052

S

PhosphoSitePlus

476355

LTP

N

HuLPr47996

PHOSPHORYLATION

1056

T

PhosphoSitePlus

476356

LTP

HTP

N

HuLPr47996

PHOSPHORYLATION

56

S

PhosphoSitePlus

15436638

LTP

N

HuLPr47996

PHOSPHORYLATION

1123

Y

PhosphoSitePlus

474491

LTP

N

HuLPr47996

PHOSPHORYLATION

1111

S

PhosphoSitePlus

5589504

HTP

N