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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr48189

Uniprot ID

VAMP5_HUMAN

Uniprot Acc

O95183;Q9P0T2;

Protein name

Vesicle-associated membrane protein 5

Comment

FUNCTION:May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking.||SUBCELLULAR LOCATION:Cell membrane; Single-pass type IV membrane protein (Probable). Endomembrane system; Single-pass type IV membrane protein (Probable). Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein (Probable). Note=Associated with the plasma membrane as well as intracellular perinuclear and peripheral vesicular structures of myotubes. Associated with the trans-Golgi, but not with the cis-Golgi apparatus (By similarity).||INDUCTION:During myogenesis.||SIMILARITY:Belongs to the synaptobrevin family.||SIMILARITY:Contains 1 v-SNARE coiled-coil homology domain.

Subcellular localization

Cell membrane;Single-pass type IV membrane protein(Probable).Endomembrane system;Single-pass type IV membrane protein(Probable).Golgi apparatus, trans-Golgi network membrane;Single-pass type IV membrane protein(Probable).

Gene name

vesicle-associated membrane protein 5 (myobrevin)

Protein sequence

MAGIELERCQQQANEVTEIMRNNFGKVLERGVKLAELQQR SDQLLDMSSTFNKTTQNLAQKKCWENIRYRICVGLVVVG VLLIILIVLLVVFLPQSSDSSSAPRTQDAGIASGPGN

Database cross reference

RefSeq Protein accession:NP_006625
RefSeq Protein gi:5730112

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0012505;C:endomembrane system;IEA:UniProtKB-SubCell.

GO-P

GO:0030154;P:cell differentiation;IEA:UniProtKB-KW. GO:0016192;P:vesicle-mediated transport;IEA:InterPro.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr48189

ACETYLATION

26

K

PhosphoSitePlus

14320206

LTP

N

HuLPr48189

PHOSPHORYLATION

48

S

PhosphoSitePlus

4148918

LTP

N

HuLPr48189

PHOSPHORYLATION

49

S

PhosphoSitePlus

4148922

LTP

N

HuLPr48189

PHOSPHORYLATION

50

T

PhosphoSitePlus

4148926

LTP

N

HuLPr48189

PHOSPHORYLATION

41

S

PhosphoSitePlus

469967

LTP

N

Pathway

Pathway name

IL2