Protein basic information
| LiverAtlas Protein ID |
HuLPr48236 |
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Uniprot ID |
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Uniprot Acc |
Q14119; |
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Protein name |
Vascular endothelial zinc finger 1 |
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Comment |
FUNCTION:Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3.||SUBUNIT:Interacts with ARHGAP22 (By similarity).||SUBCELLULAR LOCATION:Nucleus.||TISSUE SPECIFICITY:Ubiquitously expressed. Highest levels in skeletal muscle and kidney.||SIMILARITY:Belongs to the krueppel C2H2-type zinc-finger protein family.||SIMILARITY:Contains 6 C2H2-type zinc fingers. |
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Subcellular localization |
Nucleus. |
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Gene name |
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Protein sequence
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MEANWTAFLFQAHEASHHQQQAAQNSLLPLLSSAVEPPDQ KPLLPIPITQKPQGAPETLKDAIGIKKEKPKTSFVCTYC SKAFRDSYHLRRHESCHTGIKLVSRPKKTPTTVVPLIST IAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAM PVTQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSH SDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCS VCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKD RLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQS INCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQQ QQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAA TTPVTLTTPFSITSSVSSGTMSNPVTVAAAMSMRSPVNV SSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTP VTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESM PFLPQALPTSPPW |
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Database cross reference |
RefSeq Protein accession:NP_009077
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Ontology annotation
| GO-C |
GO:0005634;C:nucleus;IDA:HPA. |
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GO-F |
GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0003704;F:specific RNA polymerase II transcription factor activity;TAS:ProtInc. GO:0008270;F:zinc ion binding;IEA:InterPro. |
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GO-P |
GO:0006968;P:cellular defense response;TAS:ProtInc. GO:0006357;P:regulation of transcription from RNA polymerase II promoter;TAS:ProtInc. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |
Pathway
| Pathway name | |
| Pathway name |
