Protein basic information
LiverAtlas Protein ID |
HuLPr48244 |
Uniprot ID |
|
Uniprot Acc |
Q14135;B4DTS7;Q7L5V0;Q9BQ78; |
Protein name |
Transcription cofactor vestigial-like protein 4 |
Comment |
FUNCTION:May act as a specific coactivator for the mammalian TEFs (By similarity).||SUBUNIT:Interacts with TEFs (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=6; Name=1; IsoId=Q14135-1; Sequence=Displayed; Name=2; IsoId=Q14135-2; Sequence=VSP 010776; Name=3; IsoId=Q14135-3; Sequence=VSP 040213, VSP 040214; Note=Probable target of nonsense-mediated mRNA decay; Name=4; IsoId=Q14135-4; Sequence=VSP 040212; Name=5; IsoId=Q14135-5; Sequence=VSP 040210, VSP 040216; Name=6; IsoId=Q14135-6; Sequence=VSP 040211, VSP 040215;||SIMILARITY:Belongs to the vestigial family.||SEQUENCE CAUTION:Sequence=AAH03038.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAA09470.3; Type=Erroneous initiation; Note=Translation N-terminally shortened; |
Subcellular localization |
Nucleus(By similarity). |
Gene name |
|
Protein sequence
|
METPLDVLSRAASLVHADDEKREAALRGEPRMQTLPVASA LSSHRTGPPPISPSKRKFSMEPGDEDLDCDNDHVSKMSR IFNPHLNKTANGDCRRDPRERSRSPIERAVAPTMSLHGS HLYTSLPSLGLEQPLALTKNSLDASRPAGLSPTLTPGER QQNRPSVITCASAGARNCNLSHCPIAHSGCAAPGPASYR RPPSAATTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITG SVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPAS PSAHMVSHSHSPSVVS |
Database cross reference |
RefSeq Protein accession:NP_001121691
|
Ontology annotation
GO-C |
GO:0005634;C:nucleus;IEA:UniProtKB-SubCell. |
GO-P |
GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |
Post-translational modification
LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
HuLPr48244 |
PHOSPHORYLATION |
149 |
S |
Phospho-ELM |
HTP |
N |
||
HuLPr48244 |
PHOSPHORYLATION |
153 |
T |
Phospho-ELM |
HTP |
N |
||
HuLPr48244 |
PHOSPHORYLATION |
52 |
S |
Phospho-ELM |
HTP |
N |
||
HuLPr48244 |
PHOSPHORYLATION |
290 |
S |
PhosphoSitePlus |
HTP |
N |
||
HuLPr48244 |
PHOSPHORYLATION |
274 |
S |
PhosphoSitePlus |
LTP |
N |
||
HuLPr48244 |
PHOSPHORYLATION |
59 |
S |
PhosphoSitePlus |
LTP |
N |
||
HuLPr48244 |
PHOSPHORYLATION |
52 |
S |
PhosphoSitePlus |
HTP |
N |
||
HuLPr48244 |
PHOSPHORYLATION |
149 |
S |
PhosphoSitePlus |
LTP |
N |
||
HuLPr48244 |
PHOSPHORYLATION |
153 |
T |
PhosphoSitePlus |
LTP |
N |