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Protein basic information

LiverAtlas Protein ID

HuLPr48244

Uniprot ID

VGLL4_HUMAN

Uniprot Acc

Q14135;B4DTS7;Q7L5V0;Q9BQ78;

Protein name

Transcription cofactor vestigial-like protein 4

Comment

FUNCTION:May act as a specific coactivator for the mammalian TEFs (By similarity).||SUBUNIT:Interacts with TEFs (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=6; Name=1; IsoId=Q14135-1; Sequence=Displayed; Name=2; IsoId=Q14135-2; Sequence=VSP 010776; Name=3; IsoId=Q14135-3; Sequence=VSP 040213, VSP 040214; Note=Probable target of nonsense-mediated mRNA decay; Name=4; IsoId=Q14135-4; Sequence=VSP 040212; Name=5; IsoId=Q14135-5; Sequence=VSP 040210, VSP 040216; Name=6; IsoId=Q14135-6; Sequence=VSP 040211, VSP 040215;||SIMILARITY:Belongs to the vestigial family.||SEQUENCE CAUTION:Sequence=AAH03038.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAA09470.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Subcellular localization

Nucleus(By similarity).

Gene name

vestigial like 4 (Drosophila)

Protein sequence

METPLDVLSRAASLVHADDEKREAALRGEPRMQTLPVASA LSSHRTGPPPISPSKRKFSMEPGDEDLDCDNDHVSKMSR IFNPHLNKTANGDCRRDPRERSRSPIERAVAPTMSLHGS HLYTSLPSLGLEQPLALTKNSLDASRPAGLSPTLTPGER QQNRPSVITCASAGARNCNLSHCPIAHSGCAAPGPASYR RPPSAATTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITG SVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPAS PSAHMVSHSHSPSVVS

Database cross reference

RefSeq Protein accession:NP_001121691
RefSeq Protein gi:190014593

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr48244

PHOSPHORYLATION

149

S

Phospho-ELM

41226

HTP

N

HuLPr48244

PHOSPHORYLATION

153

T

Phospho-ELM

41228

HTP

N

HuLPr48244

PHOSPHORYLATION

52

S

Phospho-ELM

41227

HTP

N

HuLPr48244

PHOSPHORYLATION

290

S

PhosphoSitePlus

11001610

HTP

N

HuLPr48244

PHOSPHORYLATION

274

S

PhosphoSitePlus

458220

LTP

N

HuLPr48244

PHOSPHORYLATION

59

S

PhosphoSitePlus

10153634

LTP

N

HuLPr48244

PHOSPHORYLATION

52

S

PhosphoSitePlus

478547

HTP

N

HuLPr48244

PHOSPHORYLATION

149

S

PhosphoSitePlus

3195941

LTP

N

HuLPr48244

PHOSPHORYLATION

153

T

PhosphoSitePlus

3195944

LTP

N