Protein basic information
| LiverAtlas Protein ID |
HuLPr48368 |
|
Uniprot ID |
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Uniprot Acc |
Q8IZQ1;Q4W5K5;Q6P0Q5;Q8N1T2;Q8NAV6;Q96BS7;Q96D33;Q96N85;Q9Y2J7; |
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Protein name |
WD repeat and FYVE domain-containing protein 3 |
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Comment |
INTERACTION:Q9H1Y0:ATG5; NbExp=2; IntAct=EBI-1569256, EBI-1047414; P42858:HTT; NbExp=1; IntAct=EBI-1569256, EBI-466029;||SUBCELLULAR LOCATION:Membrane; Peripheral membrane protein; Cytoplasmic side. Note=Co-localizes with autophagic structures in starved cells.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8IZQ1-1; Sequence=Displayed; Name=2; IsoId=Q8IZQ1-2; Sequence=VSP 019475;||TISSUE SPECIFICITY:Ubiquitous.||SIMILARITY:Contains 1 BEACH domain.||SIMILARITY:Contains 1 FYVE-type zinc finger.||SIMILARITY:Contains 5 WD repeats.||SEQUENCE CAUTION:Sequence=AAH13377.1; Type=Erroneous initiation; Sequence=AAH15214.2; Type=Erroneous initiation; Sequence=BAB71020.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing; Sequence=BAC04455.1; Type=Erroneous initiation; |
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Subcellular localization |
Membrane;Peripheral membrane protein;Cytoplasmic side. |
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Gene name |
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Protein sequence
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MNMVKRIMGRPRQEECSPQDNALGLMHLRRLFTELCHPPR HMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQ FTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCL YLFFDLPHVPEAVGGAQNELPLAERRGLLQKVFVQILVK LCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSA GEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDL SPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFL CDLLLRLEQAKEAESKDALKDLVNLITSLTTYGVSELKP AGITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAF LKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQF AEKISKLPEVQNKYFEMLEFVVFSLNYIPCKELISVSIL LKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEV MVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLAL LVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCR QHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKT DILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERS LSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANS HFFKTEIQYEKLADAVRFLGCFSDLRKISAMNVFPSNTQ PFQRLLEEDVISIESVSPTLRHCSKLFIYLYKVATDSFD SRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPP VYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLL ASVGSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEP MVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPE MRSSMITSLEGLGTDNVFSLHEDN |
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Database cross reference |
RefSeq Protein accession:NP_055806
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver;French Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0044444;C:cytoplasmic part;IDA:MGI. GO:0019898;C:extrinsic to membrane;IDA:MGI. GO:0005635;C:nuclear envelope;IDA:MGI. |
|
GO-F |
GO:0005545;F:1-phosphatidylinositol binding;IDA:MGI. GO:0005515;F:protein binding;IPI:IntAct. GO:0008270;F:zinc ion binding;IEA:InterPro. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr48368 |
PHOSPHORYLATION |
1011 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
2490 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
2492 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
813 |
Y |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
815 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
817 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
818 |
T |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
822 |
Y |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
465 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
467 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
474 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
271 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
262 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
817 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
3339 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
2490 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
815 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
818 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
813 |
Y |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
822 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
1696 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
1699 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48368 |
PHOSPHORYLATION |
653 |
Y |
PhosphoSitePlus |
HTP |
N |
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