Protein basic information
| LiverAtlas Protein ID |
HuLPr48592 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q9ULM3;A7E2B9;D3DNS9;Q641P6;Q9NW96; |
|
Protein name |
YEATS domain-containing protein 2 |
|
Comment |
FUNCTION:Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.||SUBUNIT:Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1.||SUBCELLULAR LOCATION:Nucleus (Probable).||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.||SIMILARITY:Contains 1 YEATS domain.||SEQUENCE CAUTION:Sequence=BAA86511.1; Type=Erroneous initiation; |
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Subcellular localization |
Nucleus(Probable). |
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Gene name |
|
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Protein sequence
|
MSGIKRTIKETDPDYEDVSVALPNKRHKAIENSARDAAVQ KIETIIKEQFALEMKNKEHEIEVIDQRLIEARRMMDKLR ACIVANYYASAGLLKVSEGSKTCDTMVFNHPAIKKFLES PSRSSSPANQRAETPSANHSESDSLSQHNDFLSDKDNNS NMDIEERLSNNMEQRPSRNTGRDTSRITGSHKTEQRNAD LTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWM VYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPP FHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTY TGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAP PSLPLTIPAPVKASSPIKQSHEPVPDTSVEKGFPASTEA ERHTPFYALPSSLERTPTKMTTSQKVTFCSHGNSAFQPI ASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPIST PSPSPLPRTPTSTPVHVKQGTAGSVINNPYVIMDKQPGQ VIGATTPSTGSPTNKISTASQVSQGTGSPVPKIHGSSFV TSTVKQEDSLFASMPPLCPIGSHPKVQSPKPITGGLGAF TKVIIKQEPGEAPHVPATGAASQSPLPQYVTVKGGHMIA VSPQKQVITPGEGIAQSAKVQPSKVVGVPVGSALPSTVK QAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVS GGGGTIVAQPVQTLTKAQVTAAGPQKSGSQGSVMATLQL PATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGA ILRATNNANLQSGSAASGGSGAGGGGGGGGGGGSGSGGG GSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQ GTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQT LKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQ LSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMA PVSSSTVSSVTKTSGQQQVCVSQA |
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Database cross reference |
RefSeq Protein accession:NP_060493
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Liver relevance
|
HLPP validation |
Yes/No |
Yes |
|
Project name |
Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005671;C:Ada2/Gcn5/Ada3 transcription activator complex;IDA:BHF-UCL. |
|
GO-F |
GO:0016566;F:specific transcriptional repressor activity;IDA:BHF-UCL. GO:0017025;F:TBP-class protein binding;IPI:BHF-UCL. |
|
GO-P |
GO:0043966;P:histone H3 acetylation;IDA:BHF-UCL. GO:0010553;P:negative regulation of gene-specific transcription from RNA polymerase II promoter;IDA:BHF-UCL. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr48592 |
PHOSPHORYLATION |
118 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
144 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
367 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
521 |
T |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
447 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
465 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
519 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
627 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
471 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
124 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
120 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
463 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
473 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
478 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
575 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
765 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
1352 |
Y |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
144 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
1122 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
15 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
1131 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
1134 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
1135 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
536 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
118 |
S |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
447 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
465 |
S |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr48592 |
PHOSPHORYLATION |
519 |
S |
PhosphoSitePlus |
HTP |
N |
|
