HuLPr48620

Uniprot ID

YIPF5_HUMAN

Uniprot Acc

Q969M3;D3DQF5;Q4VSN6;Q53EX4;Q8NHE5;Q9H338;Q9H3U4;

Protein name

Protein YIPF5

Comment

FUNCTION:Plays a role in transport between endoplasmic reticulum and Golgi.||SUBUNIT:Interacts with the COPII coat components Sec23 (SEC23A and/or SEC23B) and Sec24 (SEC24A and/or SEC24B). Interacts with YIF1A. May interact with RAB1A.||SUBCELLULAR LOCATION:Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi- pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle. Note=Enriched at the endoplasmic reticulum exit sites. Incorporated into COPII coated vesicles.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q969M3-1; Sequence=Displayed; Name=2; Synonyms=D; IsoId=Q969M3-2; Sequence=VSP 018253; Name=3; Synonyms=I; IsoId=Q969M3-3; Sequence=VSP 018254;||TISSUE SPECIFICITY:Ubiquitously expressed. Highly expressed in coronary smooth muscles.||INDUCTION:By TGFB1.||SIMILARITY:Belongs to the YIP1 family.

Subcellular localization

Endoplasmic reticulum membrane;Multi-pass membrane protein.Golgi apparatus, Golgi stack membrane;Multi- pass membrane protein.Cytoplasmic vesicle, COPII-coated vesicle.

Gene name

Yip1 domain family, member 5

Protein sequence

MSGFENLNTDFYQTSYSIDDQSQQSYDYGGSGGPYSKQYA GYDYSQQGRFVPPDMMQPQQPYTGQIYQPTQAYTPASPQ PFYGNNFEDEPPLLEELGINFDHIWQKTLTVLHPLKVAD GSIMNETDLAGPMVFCLAFGATLLLAGKIQFGYVYGISA IGCLGMFCLLNLMSMTGVSFGCVASVLGYCLLPMILLSS FAVIFSLQGMVGIILTAGIIGWCSFSASKIFISALAMEG QQLLVAYPCALLYGVFALISVF

Database cross reference

RefSeq Protein accession:NP_001020118
RefSeq Protein gi:68226422

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

GO:0005789;C:endoplasmic reticulum membrane;IEA:UniProtKB-SubCell. GO:0030134;C:ER to Golgi transport vesicle;IEA:UniProtKB-SubCell. GO:0032580;C:Golgi cisterna membrane;IEA:UniProtKB-SubCell. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-P

GO:0015031;P:protein transport;IEA:UniProtKB-KW. GO:0016192;P:vesicle-mediated transport;IEA:UniProtKB-KW.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr48620

PHOSPHORYLATION

39

Y

Phospho-ELM

4710

HTP

N

HuLPr48620

PHOSPHORYLATION

42

Y

Phospho-ELM

4711

HTP

N

HuLPr48620

PHOSPHORYLATION

44

Y

Phospho-ELM

4712

HTP

N

HuLPr48620

PHOSPHORYLATION

26

Y

PhosphoSitePlus

464504

LTP

HTP

N

HuLPr48620

PHOSPHORYLATION

67

Y

PhosphoSitePlus

464506

HTP

N

HuLPr48620

PHOSPHORYLATION

39

Y

PhosphoSitePlus

449674

HTP

N

HuLPr48620

PHOSPHORYLATION

44

Y

PhosphoSitePlus

449675

LTP

N

HuLPr48620

PHOSPHORYLATION

42

Y

PhosphoSitePlus

451746

LTP

N