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Protein basic information

LiverAtlas Protein ID

HuLPr48751

Uniprot ID

ZBT20_HUMAN

Uniprot Acc

Q9HC78;Q63HP6;Q8N6R5;Q9Y410;

Protein name

Zinc finger and BTB domain-containing protein 20

Comment

FUNCTION:May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses.||SUBUNIT:Can homodimerize. Binds to DNA.||SUBCELLULAR LOCATION:Nucleus (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9HC78-1; Sequence=Displayed; Name=2; IsoId=Q9HC78-2; Sequence=VSP 032503;||TISSUE SPECIFICITY:Expressed in spleen, lymph node, thymus, peripheral blood leukocytes, and fetal liver.||SIMILARITY:Contains 1 BTB (POZ) domain.||SIMILARITY:Contains 5 C2H2-type zinc fingers.

Subcellular localization

Nucleus(By similarity).

Gene name

zinc finger and BTB domain containing 20

Protein sequence

MLERKKPKTAENQKASEENEITQPGGSSAKPGLPCLNFEA VLSPDPALIHSTHSLTNSHAHTGSSDCDISCKGMTERIH SINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAH RCVLAAGSPFFQDKLLLGYSDIEIPSVVSVQSVQKLIDF MYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQN VGDVFPGIQDSGQDTPRGTPESGTSGQSSDTESGYLQSH PQHSVDRIYSALYACSMQNGSGERSFYSGAVVSHHETAL GLPRDHHMEDPSWITRIHERSQQMERYLSTTPETTHCRK QPRPVRIQTLVGNIHIKQEMEDDYDYYGQQRVQILERNE SEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVE QQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGA SSPERSNEVEMDSTVITVSNSSDKSVLQQPSVNTSIGQP LPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYL PALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGL STFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKT FTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLIKHM VTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYEC YICKKKFSHKTLLERHVALHSASNGTPPAGTPPGARAGP PGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMHVSDG

Database cross reference

RefSeq Protein accession:NP_001157814
RefSeq Protein gi:257900533

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IDA:HPA.

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr48751

PHOSPHORYLATION

461

S

PhosphoSitePlus

14314300

HTP

N

HuLPr48751

PHOSPHORYLATION

472

S

PhosphoSitePlus

14314301

HTP

N

HuLPr48751

PHOSPHORYLATION

464

T

PhosphoSitePlus

14314302

HTP

N

HuLPr48751

PHOSPHORYLATION

465

S

PhosphoSitePlus

14314303

HTP

N

HuLPr48751

PHOSPHORYLATION

304

T

PhosphoSitePlus

485276

LTP

N

HuLPr48751

PHOSPHORYLATION

309

T

PhosphoSitePlus

485277

HTP

N