Protein basic information
| LiverAtlas Protein ID |
HuLPr48759 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q8NAP3;D3DNF6; |
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Protein name |
Zinc finger and BTB domain-containing protein 38 |
|
Comment |
FUNCTION:Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity).||POLYMORPHISM:Genetic variations in ZBTB38 define the stature quantitative trait locus 10 (STQTL10) [MIM:612221]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits.||SIMILARITY:Contains 1 BTB (POZ) domain.||SIMILARITY:Contains 10 C2H2-type zinc fingers.||SEQUENCE CAUTION:Sequence=BAC03868.1; Type=Frameshift; Positions=147; |
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Subcellular localization |
Nucleus(By similarity). |
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Gene name |
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Protein sequence
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MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVE DTKFKAHSNVLAASSLYFKNIFWSHTICISSHVLELDDL KAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISF LEDLTDRNFSNSPGPYVFCITEKGVVKEEKNEKRHEEPA ITNGPRITNAFSIIETENSNNMFSPLDLRASFKKVSDSM RTASLCLERTDVCHEAEPVRTLAEHSYAVSSVAEAYRSQ PVREHDGSSPGNTGKENCEALAAKPKTCRKPKTFSIPQD SDSATENIPPPPVSNLEVNQERSPQPAAVLTRSKSPNNE GDVHFSREDENQSSDVPGPPAAEVPPLVYNCSCCSKAFD SSTLLSAHMQLHKPTQEPLVCKYCNKQFTTLNRLDRHEQ ICMRSSHMPIPGGNQRFLENYPTIGQNGGSFTGPEPLLS ENRIGEFSSTGSTLPDTDHMVKFVNGQMLYSCVVCKRSY VTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEI WHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSI SKKTANGGLKPSVYPYKLYRLLPMKCKRAPYKSYRNSSY ENARENSQMNESAPGTYVVQNPHSSELPTLNFQDTVNTL TNSPAIPLETSACQDIPTSANVQNAEGTKWGEEALKMDL DNNFYSTEVSVSSTENAVSSDLRAGDVPVLSLSNSSENA ASVISYSGSAPSVIVHSSQFSSVIMHSNAIAAMTSSNHR AFSDPAVSQSLKDDSKPEPDKVGRFASRPKSIKEKKKTT SHTRGEIPEESNYVADPGGSLSKTTNIAEETSKIETYIA KPALPGTSTNSNVAPLCQITVKIGNEAIVKRHILGSKLF YKRGRRPKYQMQEEPLPQGNDPEPSGDSPLGLCQSECME MSEVFDDASDQDSTDKPWRPYYNYKPKKKSRQLKKMRKV NWRKEHGNRSPSHKCKYPAELDCAVGKAPQDKPFEEEET KEMPKLQCELCDGDKAVGAGNQGR |
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Database cross reference |
RefSeq Protein accession:NP_001073881
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Ontology annotation
| GO-C |
GO:0005634;C:nucleus;ISS:UniProtKB. |
|
GO-F |
GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0003700;F:sequence-specific DNA binding transcription factor activity;ISS:UniProtKB. GO:0008270;F:zinc ion binding;IEA:InterPro. |
|
GO-P |
GO:0045944;P:positive regulation of transcription from RNA polymerase II promoter;ISS:UniProtKB. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr48759 |
PHOSPHORYLATION |
130 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr48759 |
PHOSPHORYLATION |
309 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr48759 |
SUMOYLATION |
43 |
K |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48759 |
PHOSPHORYLATION |
307 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48759 |
PHOSPHORYLATION |
309 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48759 |
PHOSPHORYLATION |
130 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48759 |
PHOSPHORYLATION |
181 |
S |
PhosphoSitePlus |
LTP |
N |
|
