Protein basic information
| LiverAtlas Protein ID |
HuLPr48872 |
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Uniprot ID |
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Uniprot Acc |
Q96KR1;B2RNR5;Q05C08;Q3B7X5;Q6P5A3;Q86UA0;Q9H6V4;Q9NTI1;Q9Y687; |
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Protein name |
Zinc finger RNA-binding protein |
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Comment |
FUNCTION:Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA (By similarity).||SUBUNIT:Found in a cytoplasmic RNP complex with STAU2. Interacts with STAU2. Does not interact with STAU1 (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity). Cytoplasm (By similarity). Cytoplasmic granule (By similarity). Chromosome (By similarity). Note=Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules (By similarity).||TISSUE SPECIFICITY:Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney.||SIMILARITY:Contains 1 DZF domain.||SEQUENCE CAUTION:Sequence=AAD40385.1; Type=Erroneous initiation; Sequence=AAH30540.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=AAI07418.1; Type=Miscellaneous discrepancy |
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Subcellular localization |
Nucleus(By similarity).Cytoplasm(By similarity).Cytoplasmic granule(By similarity).Chromosome(By similarity). |
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Gene name |
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Protein sequence
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MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAAA AAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAA YAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHTATDY GYTQRQQEAPPPPPPATTQNYQDSYSYVRSTAPAVAYDS KQYYQQPTATAAAVAAAAQPQPSVAETYYQTAPKAGYSQ GATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQ PVAAAATVVPSYTQSATYSTTAVTYSGTSYSGYEAAVYS AASSYYQQQQQQQKQAAAAAAAAAATAAWTGTTFTKKAP FQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEG QKHKKKEAALKASQNTSSSNSSTRGTQNQLRCELCDVSC TGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVSQ ATSSTAVSASKPTASPSSIAANNCTVNTSSVATSSMKGL TTTGNSSLNSTSNTKVSAVPTNMAAKKTSTPKINFVGGN KLQSTGNKAEDIKGTECVKSTPVTSAVQIPEVKQDTVSE PVTPASLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKL CECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPS IRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEE DMYWRRMEEEQHHWDDRRRMPDGGYPHGPPGPLGLLGVR PGMPPQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQ AVQKIVSITERALKLVSDSLSEHEKNKNKEGDDKKEGGK DRALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKTL LSRIAENLPKQLAVISPEKYDIKCAVSEAAIILNSCVEP KMQVTITLTSPIIREENMREGDVTSGMVKDPPDVLDRQK CLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVP TWSDFPSWAMELLVEKAISSASSPQSPGDALRRVFECIS SGIILKGSPGLLDPCEKDPFDTLA |
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Database cross reference |
RefSeq Protein accession:NP_057191
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver; |
Ontology annotation
| GO-C |
GO:0005694;C:chromosome;IEA:UniProtKB-SubCell. GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell. GO:0005634;C:nucleus;IDA:HPA. |
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GO-F |
GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0003723;F:RNA binding;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro. |
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GO-P |
GO:0007275;P:multicellular organismal development;IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
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HuLPr48872 |
PHOSPHORYLATION |
201 |
Y |
PhosphoSitePlus |
LTP |
N |
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HuLPr48872 |
PHOSPHORYLATION |
1054 |
S |
PhosphoSitePlus |
LTP |
N |
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HuLPr48872 |
ACETYLATION |
509 |
K |
PhosphoSitePlus |
HTP |
N |
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HuLPr48872 |
ACETYLATION |
910 |
K |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48872 |
ACETYLATION |
317 |
K |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr48872 |
PHOSPHORYLATION |
186 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48872 |
PHOSPHORYLATION |
610 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr48872 |
PHOSPHORYLATION |
667 |
Y |
PhosphoSitePlus |
LTP |
N |
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