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Protein basic information

LiverAtlas Protein ID

HuLPr49036

Uniprot ID

ZN343_HUMAN

Uniprot Acc

Q6P1L6;Q5JXU8;Q5JXU9;Q8N8F2;Q96EX8;Q96NA5;Q9BQB0;

Protein name

Zinc finger protein 343

Comment

FUNCTION:May be involved in transcriptional regulation.||SUBCELLULAR LOCATION:Nucleus (Potential).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q6P1L6-1; Sequence=Displayed; Name=2; IsoId=Q6P1L6-2; Sequence=VSP 016028; Note=No experimental confirmation available; Name=3; IsoId=Q6P1L6-3; Sequence=VSP 016029, VSP 016030; Note=No experimental confirmation available;||SIMILARITY:Belongs to the krueppel C2H2-type zinc-finger protein family.||SIMILARITY:Contains 12 C2H2-type zinc fingers.||SIMILARITY:Contains 1 KRAB domain.

Subcellular localization

Nucleus(Potential).

Gene name

zinc finger protein 343

Protein sequence

MMLPYPSALGDQYWEEILLPKNGENVETMKKLTQNHKAKG LPSNDTDCPQKKEGKAQIVVPVTFRDVTVIFTEAEWKRL SPEQRNLYKEVMLENYRNLLSLAEPKPEIYTCSSCLLAF SCQQFLSQHVLQIFLGLCAENHFHPGNSSPGHWKQQGQQ YSHVSCWFENAEGQERGGGSKPWSARTEERETSRAFPSP LQRQSASPRKGNMVVETEPSSAQRPNPVQLDKGLKELET LRFGAINCREYEPDHNLESNFITNPRTLLGKKPYICSDC GRSFKDRSTLIRHHRIHSMEKPYVCSECGRGFSQKSNLS RHQRTHSEEKPYLCRECGQSFRSKSILNRHQWTHSEEKP YVCSECGRGFSEKSSFIRHQRTHSGEKPYVCLECGRSFC DKSTLRKHQRIHSGEKPYVCRECGRGFSQNSDLIKHQRT HLDEKPYVCRECGRGFCDKSTLIIHERTHSGEKPYVCGE CGRGFSRKSLLLVHQRTHSGEKHYVCRECRRGFSQKSNL IRHQRTHSNEKPYICRECGRGFCDKSTLIVHERTHSGEK PYVCSECGRGFSRKSLLLVHQRTHSGEKHYVCRECGRGFSHKSNLIRHQRTH

Database cross reference

RefSeq Protein accession:NP_077301
RefSeq Protein gi:31563521

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;Chinese Liver;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW.