Protein basic information
LiverAtlas Protein ID |
HuLPr49065 |
Uniprot ID |
|
Uniprot Acc |
Q8TAQ5;B2RDY6; |
Protein name |
Zinc finger protein 420 |
Comment |
FUNCTION:May be involved in transcriptional regulation.||SUBCELLULAR LOCATION:Nucleus (Potential).||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.||SIMILARITY:Contains 19 C2H2-type zinc fingers.||SIMILARITY:Contains 1 KRAB domain. |
Subcellular localization |
Nucleus(Potential). |
Gene name |
|
Protein sequence
|
MARKLVMFRDVAIDFSQEEWECLDSAQRDLYRDVMLENYS NLVSLDLPSRCASKDLSPEKNTYETELSQWEMSDRLENC DLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKMS IFNQHTYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQH QSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYA CKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRS SQLTRHQKVHTGEKPYECKECGKAFTQNSQLTLHQRLHT GEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECG KAFICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQ HQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPY ECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNR GSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIH TGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKEC RMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLI QHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKP YECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFT QSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRI HISEKSFEYKECGIDFSHGSQVYM |
Database cross reference |
RefSeq Protein accession:NP_653290
|
Liver relevance
HLPP validation |
Yes/No |
Yes |
Project name |
Chinese Liver;Human Fetal Liver;Human Liver Organelles; |
Ontology annotation
GO-C |
GO:0005634;C:nucleus;IEA:UniProtKB-SubCell. |
GO-F |
GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro. |
GO-P |
GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |
Post-translational modification
LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
HuLPr49065 |
PHOSPHORYLATION |
488 |
S |
Phospho-ELM |
HTP |
N |
||
HuLPr49065 |
PHOSPHORYLATION |
302 |
T |
PhosphoSitePlus |
LTP |
N |
||
HuLPr49065 |
PHOSPHORYLATION |
488 |
S |
PhosphoSitePlus |
LTP |
N |
||
HuLPr49065 |
PHOSPHORYLATION |
40 |
S |
PhosphoSitePlus |
LTP |
N |
||
HuLPr49065 |
PHOSPHORYLATION |
39 |
Y |
PhosphoSitePlus |
HTP |
N |
||
HuLPr49065 |
PHOSPHORYLATION |
68 |
S |
PhosphoSitePlus |
HTP |
N |