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Protein basic information

LiverAtlas Protein ID

HuLPr49065

Uniprot ID

ZN420_HUMAN

Uniprot Acc

Q8TAQ5;B2RDY6;

Protein name

Zinc finger protein 420

Comment

FUNCTION:May be involved in transcriptional regulation.||SUBCELLULAR LOCATION:Nucleus (Potential).||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.||SIMILARITY:Contains 19 C2H2-type zinc fingers.||SIMILARITY:Contains 1 KRAB domain.

Subcellular localization

Nucleus(Potential).

Gene name

zinc finger protein 420

Protein sequence

MARKLVMFRDVAIDFSQEEWECLDSAQRDLYRDVMLENYS NLVSLDLPSRCASKDLSPEKNTYETELSQWEMSDRLENC DLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKMS IFNQHTYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQH QSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYA CKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRS SQLTRHQKVHTGEKPYECKECGKAFTQNSQLTLHQRLHT GEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECG KAFICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQ HQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPY ECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNR GSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIH TGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKEC RMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLI QHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKP YECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFT QSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRI HISEKSFEYKECGIDFSHGSQVYM

Database cross reference

RefSeq Protein accession:NP_653290
RefSeq Protein gi:22095393

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Fetal Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr49065

PHOSPHORYLATION

488

S

Phospho-ELM

22000

HTP

N

HuLPr49065

PHOSPHORYLATION

302

T

PhosphoSitePlus

1220644

LTP

N

HuLPr49065

PHOSPHORYLATION

488

S

PhosphoSitePlus

482065

LTP

N

HuLPr49065

PHOSPHORYLATION

40

S

PhosphoSitePlus

13831902

LTP

N

HuLPr49065

PHOSPHORYLATION

39

Y

PhosphoSitePlus

13831904

HTP

N

HuLPr49065

PHOSPHORYLATION

68

S

PhosphoSitePlus

7669300

HTP

N