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Protein basic information

LiverAtlas Protein ID

HuLPr49076

Uniprot ID

ZN436_HUMAN

Uniprot Acc

Q9C0F3;Q658I9;

Protein name

Zinc finger protein 436

Comment

FUNCTION:May be a transcriptional repressor.||SUBCELLULAR LOCATION:Nucleus.||TISSUE SPECIFICITY:Expressed in fetal brain, heart, liver, spleen, bladder, lung, skin, skeletal muscle, stomach and pancreas.||SIMILARITY:Belongs to the krueppel C2H2-type zinc-finger protein family.||SIMILARITY:Contains 12 C2H2-type zinc fingers.||SIMILARITY:Contains 1 KRAB domain.||SEQUENCE CAUTION:Sequence=BAB21801.1; Type=Erroneous initiation;

Subcellular localization

Nucleus.

Gene name

zinc finger protein 436

Protein sequence

MAATLLMAGSQAPVTFEDMAMYLTREEWRPLDAAQRDLYR DVMQENYGNVVSLDFEIRSENEVNPKQEISEDVQFGTTS ERPAENAEENPESEEGFESGDRSERQWGDLTAEEWVSYP LQPVTDLLVHKEVHTGIRYHICSHCGKAFSQISDLNRHQ KTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDC NECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLS HLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTG EKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGK NFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQH QRTHTGEKPYECNACGKSFSRSSHLITHQKIHTGEKPYE CNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQS SNLITHQRVHTGEKPYECTECEKSFSRSSALIKHKRVHTD

Database cross reference

RefSeq Protein accession:NP_001070663
RefSeq Protein gi:116089280

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW.