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Protein basic information

LiverAtlas Protein ID

HuLPr49131

Uniprot ID

ZN541_HUMAN

Uniprot Acc

Q9H0D2;Q8NDK8;

Protein name

Zinc finger protein 541

Comment

FUNCTION:Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis (By similarity).||SUBUNIT:Interacts with HDAC1 and HSPA2 (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9H0D2-1; Sequence=Displayed; Name=2; IsoId=Q9H0D2-2; Sequence=VSP 016024; Note=No experimental confirmation available; Name=3; IsoId=Q9H0D2-3; Sequence=VSP 036220; Note=No experimental confirmation available;||SIMILARITY:Contains 5 C2H2-type zinc fingers.||SIMILARITY:Contains 1 ELM2 domain.||SIMILARITY:Contains 1 SANT domain.||SEQUENCE CAUTION:Sequence=AAI01051.1; Type=Erroneous initiation; Sequence=AAI01052.1; Type=Erroneous initiation; Sequence=AAI01053.1; Type=Erroneous initiation; Sequence=AAI01054.1; Type=Erroneous initiation; Sequence=CAB66780.1; Type=Erroneous initiation; Sequence=CAD38720.2; Type=Frameshift; Positions=473;

Subcellular localization

Nucleus(By similarity).

Gene name

zinc finger protein 541

Protein sequence

MDQYSLGDEGALPSEMHLPSFSESQGLNCSDTLNRDLGPN TRGFLYAGLSGLDPDPSLPTPDMSSEVLEDNLDTLSLYS GKDSDSVKLLEEYADSESQASLQDLGLGVLKAKEADEGG RATSGSARKGKRQHSSPQNPLLDCSLCGKVFSSASSLSK HYLTHSQERKHVCKICSKAFKRQDHLTGHMLTHQKTKPF VCIEQGCSKSYCDYRSLRRHYEVHHGLCILKEAPPEEEA CGDSPHAHESAGQPPPSSLRSLVPPEARSPGSLLPHRDL LRRIVSSIVHQKTPSPGPAPAGASDSEGRNTACPCPASS GSSSCTPAGPHAAPAALDTELPEEPCLPQKEPATDVFTA PNSRAAENGAPDPPEPEPDTALLQARSTAECWPEGGSVP ACLPLFRGQTVPASSQPSSHSFQWLRNLPGCPKSKGNNV FVVHKPSAVPSREGSESGPGPSSGSPSEESPPGPGGGLE DALPFPAALLRVPAEAPSDPRSASGEDDPCAPKKVKVDC DSFLCQNPGEPGLQEAQKAGGLPADASPLFRQLFLKSQE PLVSHEQMQVFQMITKSQRIFSHAQVAAVSSQLPAPEGK PAALRPLQGPWPQQPPPLAPAVDSLHAGPGNPEAEGSPA RRRKTTPGVPREASPGSTRRDAKGGLKVAAVPTPLAAPS LDPSRNPDISSLAKQLRSSKGTLDLEDIFPSTGQRQTQL GGEEPPGASLPGKQAPAENGAASRITKGEKGPACSRGGG YRLLGNPRAPRFSGFRKEKAKMDMCCAASPSQVAMASFS SAGPPADPSKSKLTIFSRIQGGNIYRLPHPVKEENVAGR GNQQNGSPTDWTKPRSTFVCKNCSQMFYTEKGLSSHMCF HSDQWPSPRGKQEPQVFGTEFCKPLRQVLRPEGDRHSPP GTKKPLDPTAAAPLVVPQSIPVVPVTRHIGSMAMMEWCS RWLQATTCGSKLLQGQEKDGEERDSKESSQQRKRKKRPP PSTAGEPGPAGCHQSRLRSPMFLV

Database cross reference

RefSeq Protein accession:NP_001094889
RefSeq Protein gi:210031154

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0003677;F:DNA binding;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0030154;P:cell differentiation;IEA:UniProtKB-KW. GO:0007275;P:multicellular organismal development;IEA:UniProtKB-KW. GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0007283;P:spermatogenesis;IEA:UniProtKB-KW. GO:0006351;

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr49131

PHOSPHORYLATION

1286

S

PhosphoSitePlus

7322698

LTP

N