Protein basic information
LiverAtlas Protein ID |
HuLPr49131 |
Uniprot ID |
|
Uniprot Acc |
Q9H0D2;Q8NDK8; |
Protein name |
Zinc finger protein 541 |
Comment |
FUNCTION:Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis (By similarity).||SUBUNIT:Interacts with HDAC1 and HSPA2 (By similarity).||SUBCELLULAR LOCATION:Nucleus (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9H0D2-1; Sequence=Displayed; Name=2; IsoId=Q9H0D2-2; Sequence=VSP 016024; Note=No experimental confirmation available; Name=3; IsoId=Q9H0D2-3; Sequence=VSP 036220; Note=No experimental confirmation available;||SIMILARITY:Contains 5 C2H2-type zinc fingers.||SIMILARITY:Contains 1 ELM2 domain.||SIMILARITY:Contains 1 SANT domain.||SEQUENCE CAUTION:Sequence=AAI01051.1; Type=Erroneous initiation; Sequence=AAI01052.1; Type=Erroneous initiation; Sequence=AAI01053.1; Type=Erroneous initiation; Sequence=AAI01054.1; Type=Erroneous initiation; Sequence=CAB66780.1; Type=Erroneous initiation; Sequence=CAD38720.2; Type=Frameshift; Positions=473; |
Subcellular localization |
Nucleus(By similarity). |
Gene name |
|
Protein sequence
|
MDQYSLGDEGALPSEMHLPSFSESQGLNCSDTLNRDLGPN TRGFLYAGLSGLDPDPSLPTPDMSSEVLEDNLDTLSLYS GKDSDSVKLLEEYADSESQASLQDLGLGVLKAKEADEGG RATSGSARKGKRQHSSPQNPLLDCSLCGKVFSSASSLSK HYLTHSQERKHVCKICSKAFKRQDHLTGHMLTHQKTKPF VCIEQGCSKSYCDYRSLRRHYEVHHGLCILKEAPPEEEA CGDSPHAHESAGQPPPSSLRSLVPPEARSPGSLLPHRDL LRRIVSSIVHQKTPSPGPAPAGASDSEGRNTACPCPASS GSSSCTPAGPHAAPAALDTELPEEPCLPQKEPATDVFTA PNSRAAENGAPDPPEPEPDTALLQARSTAECWPEGGSVP ACLPLFRGQTVPASSQPSSHSFQWLRNLPGCPKSKGNNV FVVHKPSAVPSREGSESGPGPSSGSPSEESPPGPGGGLE DALPFPAALLRVPAEAPSDPRSASGEDDPCAPKKVKVDC DSFLCQNPGEPGLQEAQKAGGLPADASPLFRQLFLKSQE PLVSHEQMQVFQMITKSQRIFSHAQVAAVSSQLPAPEGK PAALRPLQGPWPQQPPPLAPAVDSLHAGPGNPEAEGSPA RRRKTTPGVPREASPGSTRRDAKGGLKVAAVPTPLAAPS LDPSRNPDISSLAKQLRSSKGTLDLEDIFPSTGQRQTQL GGEEPPGASLPGKQAPAENGAASRITKGEKGPACSRGGG YRLLGNPRAPRFSGFRKEKAKMDMCCAASPSQVAMASFS SAGPPADPSKSKLTIFSRIQGGNIYRLPHPVKEENVAGR GNQQNGSPTDWTKPRSTFVCKNCSQMFYTEKGLSSHMCF HSDQWPSPRGKQEPQVFGTEFCKPLRQVLRPEGDRHSPP GTKKPLDPTAAAPLVVPQSIPVVPVTRHIGSMAMMEWCS RWLQATTCGSKLLQGQEKDGEERDSKESSQQRKRKKRPP PSTAGEPGPAGCHQSRLRSPMFLV |
Database cross reference |
RefSeq Protein accession:NP_001094889
|
Liver relevance
HLPP validation |
Yes/No |
Yes |
Project name |
Chinese Liver;Human Liver Organelles; |
Ontology annotation
GO-C |
GO:0005634;C:nucleus;IEA:UniProtKB-SubCell. |
GO-F |
GO:0003677;F:DNA binding;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro. |
GO-P |
GO:0030154;P:cell differentiation;IEA:UniProtKB-KW. GO:0007275;P:multicellular organismal development;IEA:UniProtKB-KW. GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0007283;P:spermatogenesis;IEA:UniProtKB-KW. GO:0006351; |
Post-translational modification
LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
HuLPr49131 |
PHOSPHORYLATION |
1286 |
S |
PhosphoSitePlus |
LTP |
N |