Protein basic information
| LiverAtlas Protein ID |
HuLPr49158 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q6ZN55;Q6IPE0;Q6ZN10;Q7L5Z5;Q8NCE3;Q9H6N0; |
|
Protein name |
Zinc finger protein 574 |
|
Comment |
FUNCTION:May be involved in transcriptional regulation.||SUBCELLULAR LOCATION:Nucleus (Probable).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6ZN55-1; Sequence=Displayed; Name=2; IsoId=Q6ZN55-2; Sequence=VSP 022878; Note=No experimental confirmation available;||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.||SIMILARITY:Belongs to the krueppel C2H2-type zinc-finger protein family.||SIMILARITY:Contains 20 C2H2-type zinc fingers. |
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Subcellular localization |
Nucleus(Probable). |
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Gene name |
|
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Protein sequence
|
MTEESEETVLYIEHRYVCSECNQLYGSLEEVLMHQNSHVP QQHFELVGVADPGVTVATDTASGTGLYQTLVQESQYQCL ECGQLLMSPSQLLEHQELHLKMMAPQEAVPAEPSPKAPP LSSSTIHYECVDCKALFASQELWLNHRQTHLRATPTKAP APVVLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGATVP SAAATTTEVVTEVELLLYKCSECSQLFQLPADFLEHQAT HFPAPVPESQEPALQQEVQASSPAEVPVSQPDPLPASDH SYELRNGEAIGRDRRGRRARRNNSGEAGGAATQELFCSA CDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLD QHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPL HSCPCGKTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEEP VIGFPEPAPAETGEPEAPEPPVSEETSAGPAAPGTYRCL LCSREFGKALQLTRHQRFVHRLERRHKCSICGKMFKKKS HVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTG ERPYRCGDCGKAFTQSSTLRQHRLVHAQHFPYRCQECGV RFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVH QLVVHAGRQPHRCPSCGAAFPSSLRLREHRCAAAAAQAP RRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAKEPP APRAPRATRAPVASPAALGSTATASPAAPARRRGLECSE CKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHL KDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGER PYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEA EAAVGLAVMETAVEALPLVEAIEIYPLAEAEGVQISG |
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Database cross reference |
RefSeq Protein accession:NP_073589
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Liver relevance
|
HLPP validation |
Yes/No |
Yes |
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Project name |
French Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005634;C:nucleus;IEA:UniProtKB-SubCell. |
|
GO-F |
GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0008270;F:zinc ion binding;IEA:InterPro. |
|
GO-P |
GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr49158 |
PHOSPHORYLATION |
113 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
137 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
154 |
T |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
164 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
298 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
717 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
724 |
T |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
728 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
113 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
298 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
717 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
605 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
164 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
728 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
724 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr49158 |
PHOSPHORYLATION |
137 |
S |
PhosphoSitePlus |
HTP |
N |
|
