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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr49362

Uniprot ID

ZNF71_HUMAN

Uniprot Acc

Q9NQZ8;Q15919;Q9UC09;Q9UQD3;

Protein name

Endothelial zinc finger protein induced by tumor necrosis factor alpha

Comment

FUNCTION:May be involved in transcriptional regulation.||SUBCELLULAR LOCATION:Nucleus (Potential).||TISSUE SPECIFICITY:Highly expressed in placenta, followed by brain, testis, pancreas, heart, small intestine, muscle, uterus, prostate and peripheral blood leukocytes. Not detected in liver, lung, colon, stomach, salivary and thyroid gland.||INDUCTION:By TNF.||SIMILARITY:Belongs to the krueppel C2H2-type zinc-finger protein family.||SIMILARITY:Contains 13 C2H2-type zinc fingers.||SEQUENCE CAUTION:Sequence=AAD23608.1; Type=Erroneous initiation;

Subcellular localization

Nucleus(Potential).

Gene name

zinc finger protein 71

Protein sequence

MKELDPKNDISEDKLSVVGEATGGPTRNGARGPGSEGVWE PGSWPERPRGDAGAEWEPLGIPQGNKLLGGSVPACHELK AFANQGCVLVPPRLDDPTEKGACPPVRRGKNFSSTSDLS KPPMPCEEKKTYDCSECGKAFSRSSSLIKHQRIHTGEKP FECDTCGKHFIERSSLTIHQRVHTGEKPYACGDCGKAFS QRMNLTVHQRTHTGEKPYVCDVCGKAFRKTSSLTQHERI HTGEKPYACGDCGKAFSQNMHLIVHQRTHTGEKPYVCPE CGRAFSQNMHLTEHQRTHTGEKPYACKECGKAFNKSSSL TLHQRNHTGEKPYVCGECGKAFSQSSYLIQHQRFHIGVK PFECSECGKAFSKNSSLTQHQRIHTGEKPYECYICKKHF TGRSSLIVHQIVHTGEKPYVCGECGKAFSQSAYLIEHQR IHTGEKPYRCGQCGKSFIKNSSLTVHQRIHTGEKPYRCG ECGKTFSRNTNLTRHLRIHT

Database cross reference

RefSeq Protein accession:NP_067039
RefSeq Protein gi:11034821

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;Chinese Liver;

Ontology annotation

GO-C

GO:0005634;C:nucleus;NAS:UniProtKB.

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0003700;F:sequence-specific DNA binding transcription factor activity;NAS:UniProtKB. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;NAS:UniProtKB.