Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr49397

Uniprot ID

ZNT9_HUMAN

Uniprot Acc

Q6PML9;Q4W5B6;Q7Z5I7;Q8TBB2;Q9Y6R2;

Protein name

Zinc transporter 9

Comment

FUNCTION:Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity).||SUBUNIT:Interacts with GRIP1, ESR1 and AR (By similarity).||SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein (Potential). Nucleus.||TISSUE SPECIFICITY:Ubiquitously expressed in fetal and adult tissues and cancer cell lines.||SIMILARITY:Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.||SEQUENCE CAUTION:Sequence=AAP83846.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites; Sequence=AAY40966.1; Type=Erroneous gene model prediction;

Subcellular localization

Membrane;Multi-pass membrane protein(Potential).Nucleus.

Gene name

solute carrier family 30 (zinc transporter), member 9

Protein sequence

MLPGLAAAAAHRCSWSSLCRLRLRCRAAACNPSDRQEWQN LVTFGSFSNMVPCSHPYIGTLSQVKLYSTNVQKEGQGSQ TLRVEKVPSFETAEGIGTELKAPLKQEPLQVRVKAVLKK REYGSKYTQNNFITGVRAINEFCLKSSDLEQLRKIRRRS PHEDTESFTVYLRSDVEAKSLEVWGSPEALAREKKLRKE AEIEYRERLFRNQKILREYRDFLGNTKPRSRTASVFFKG PGKVVMVAICINGLNCFFKFLAWIYTGSASMFSEAIHSL SDTCNQGLLALGISKSVQTPDPSHPYGFSNMRYISSLIS GVGIFMMGAGLSWYHGVMGLLHPQPIESLLWAYCILAGS LVSEGATLLVAVNELRRNARAKGMSFYKYVMESRDPSTN VILLEDTAAVLGVIIAATCMGLTSITGNPLYDSLGSLGV GTLLGMVSAFLIYTNTEALLGRSIQPEQVQRLTELLEND PSVRAIHDVKATDLGLGKVRFKAEVDFDGRVVTRSYLEK QDFDQMLQEIQEVKTPEELETFMLKHGENIIDTLGAEVD RLEKELKKRNPEVRHVDLEIL

Database cross reference

RefSeq Protein accession:NP_006336
RefSeq Protein gi:57164948

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005856;C:cytoskeleton;IDA:UniProtKB. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005634;C:nucleus;IDA:UniProtKB.

GO-F

GO:0008324;F:cation transmembrane transporter activity;IEA:InterPro. GO:0000166;F:nucleotide binding;IEA:InterPro. GO:0003700;F:sequence-specific DNA binding transcription factor activity;NAS:UniProtKB.

GO-P

GO:0006289;P:nucleotide-excision repair;TAS:BHF-UCL. GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006829;P:zinc ion transport;IEA:UniProtKB-KW.