Protein basic information
| LiverAtlas Protein ID |
HuLPr49406 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q9UK55;A5Z2A5;Q6UWX9;Q86U20; |
|
Protein name |
Protein Z-dependent protease inhibitor |
|
Comment |
FUNCTION:Inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid.||SUBCELLULAR LOCATION:Secreted.||TISSUE SPECIFICITY:Expressed by the liver and secreted in plasma.||PTM:Phosphorylation sites are present in the extracelllular medium.||SIMILARITY:Belongs to the serpin family.||SEQUENCE CAUTION:Sequence=CAD62339.1; Type=Erroneous initiation;||WEB RESOURCE:Name=SeattleSNPs; URL="http://pga.gs.washington.edu/data/serpina10/"; |
|
Subcellular localization |
Secreted. |
|
Gene name |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
|
Protein sequence
|
MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSR VVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKET SNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATG PTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLE LGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR NASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDY ILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGK FASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALE DYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELL RQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVD ERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSG MLLFLGRVVNPTLL |
|
Database cross reference |
RefSeq Protein accession:NP_001094077
|
Liver relevance
|
HLPP validation |
Yes/No |
Yes |
|
Project name |
Chinese Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005576;C:extracellular region;IEA:UniProtKB-SubCell. |
|
GO-F |
GO:0004867;F:serine-type endopeptidase inhibitor activity;ISS:RefGenome. |
|
GO-P |
GO:0030162;P:regulation of proteolysis;ISS:RefGenome. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr49406 |
PHOSPHORYLATION |
297 |
T |
PhosphoSitePlus |
LTP |
N |
 
|
|
|
HuLPr49406 |
PHOSPHORYLATION |
56 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49406 |
PHOSPHORYLATION |
61 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49406 |
PHOSPHORYLATION |
292 |
Y |
PhosphoSitePlus |
LTP |
N |
|
