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Protein basic information

LiverAtlas Protein ID

HuLPr49419

Uniprot ID

ZSC18_HUMAN

Uniprot Acc

Q8TBC5;Q9BRK7;Q9H9A0;

Protein name

Zinc finger and SCAN domain-containing protein 18

Comment

FUNCTION:May be involved in transcriptional regulation.||SUBCELLULAR LOCATION:Nucleus (Potential).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8TBC5-1; Sequence=Displayed; Name=2; IsoId=Q8TBC5-2; Sequence=VSP 019497; Note=No experimental confirmation available;||SIMILARITY:Belongs to the krueppel C2H2-type zinc-finger protein family.||SIMILARITY:Contains 2 C2H2-type zinc fingers.||SIMILARITY:Contains 1 SCAN box domain.

Subcellular localization

Nucleus(Potential).

Gene name

zinc finger and SCAN domain containing 18

Protein sequence

MLPLEKAFASPRSSPAPPDLPTPGSAAGVQQEEPETIPER TPADLEFSRLRFREFVYQEAAGPHQTLARLHELCRQWLM PEARSKEQMLELLVLEQFLGILPDKVRPWVVAQYPESCK KAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHM DPLLLPGELASPSQALGAGEIPAPSETPWLSPDPLFLEQ RRVREAKTEEDGPANTEQKLKSFPEDPQHLGEWGHLDPA EENLKSYRKLLLWGYQLSQPDAASRLDTEELRLVERDPQ GSSLPEGGRRQESAGCACEEAAPAGVLPELPTEAPPGDA LADPPSGTTEEEEEQPGKAPDPQDPQDAESDSATGSQRQ SVIQQPAPDRGTAKLGTKRPHPEDGDGQSLEGVSSSGDS AGLEAGQGPGADEPGLSRGKPYACGECGEAFAWLSHLME HHSSHGGRKRYACQGCWKTFHFSLALAEHQKTHEKEKSY ALGGARGPQPSTREAQAGARAGGPPESVEGEAPPAPPEAQR

Database cross reference

RefSeq Protein accession:NP_001139014
RefSeq Protein gi:224493905

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0003700;F:sequence-specific DNA binding transcription factor activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0016032;P:viral reproduction;IEA:InterPro.