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Protein basic information

LiverAtlas Protein ID

HuLPr49426

Uniprot ID

ZSCA1_HUMAN

Uniprot Acc

Q8NBB4;Q3B798;Q6WLH8;Q86WS8;

Protein name

Zinc finger and SCAN domain-containing protein 1

Comment

FUNCTION:May be involved in transcriptional regulation.||SUBCELLULAR LOCATION:Nucleus (Potential).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8NBB4-1; Sequence=Displayed; Name=2; IsoId=Q8NBB4-2; Sequence=VSP 011953, VSP 011954; Note=Ref.1 (AAQ16582) sequence is in conflict in position: 130:R->P;||SIMILARITY:Contains 3 C2H2-type zinc fingers.||SIMILARITY:Contains 1 SCAN box domain.

Subcellular localization

Nucleus(Potential).

Gene name

zinc finger and SCAN domain containing 1

Protein sequence

MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLR FRQFQYHVASGPHLALGQLWTLCRQWLRPEARSKEQMLE LLVLEQFLGALPSKMRTWVQSQGPRSCREAASLVEDLTQ MCQQEVLVSLDSVEPQDWSFGEEEDGKSPRSQKEPSQAS ELILDAVAAAPALPEESEWLETTQLQQSLHTRAEAEAPR APGLLGSRARLPLKPSIWDEPEDLLAGPSSDLRAEGTVI SSPKGPSAQRISPRRRNRNTDQSGRHQPSLKHTKGGTQE AVAGISVVPRGPRGGRPFQCADCGMVFTWVTHFIEHQKT HREEGPFPCPECGKVFLHNSVLTEHGKIHLLEPPRKKAP RSKGPRESVPPRDGAQGPVAPRSPKRPFQCSVCGKAFPW MVHLIDHQKLHTAHGHM

Database cross reference

RefSeq Protein accession:NP_872378
RefSeq Protein gi:110431336

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0003700;F:sequence-specific DNA binding transcription factor activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0016032;P:viral reproduction;IEA:InterPro.