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Protein basic information

LiverAtlas Protein ID

HuLPr49439

Uniprot ID

ZXDB_HUMAN

Uniprot Acc

P98169;A8K151;Q9UBB3;

Protein name

Zinc finger X-linked protein ZXDB

Comment

FUNCTION:Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes (By similarity).||SUBUNIT:Self-associates. Interacts with ZXDC and CIITA (By similarity).||SUBCELLULAR LOCATION:Nucleus (Probable).||TISSUE SPECIFICITY:May be expressed in brain, heart, kidney, liver, lung, muscle and placenta.||SIMILARITY:Belongs to the ZXD family.||SIMILARITY:Contains 10 C2H2-type zinc fingers.

Subcellular localization

Nucleus(Probable).

Gene name

zinc finger, X-linked, duplicated B

Protein sequence

MEIPKLLPARGTLQGGGGGGIPAGGGRVHRGPDSPAGQVP TRRLLLLRGPQDGGPGRRREEASTASRGPGPSLLAPRTD QPSGGGGGGGDDFFLVLLDPVGGDVETAGSGQAAGPVLR EEAEEGPGLQGGESGANPAGPTALGPRCLSAVPTPAPIS APGPAAAFAGTVTIHNQDLLLRFENGVLTLATPPPHAWE PGAAPAQQPGCLIAPQAGFPHAAHPGDCPELPPDLLLAE PAEPAPAPAPEEEAEGPAAALGPRGPLGSGPGVVLYLCP EAQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGW TFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLK AHMKGHEQENSFKCEVCEESFPTQAKLSAHQRSHFEPER PYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPG CSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMS KLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITH LGTKPFVCPVAGCCARFSARSSLYIHSKKHLQDVDTWKS RCPISSCNKLFTSKHSMKTHMVKRHKVGQDLLAQLEAAN SLTPSSELTSQRQNDLSDAEIVSLFSDVPDSTSAALLDT ALVNSGILTIDVASVSSTLAGHLPANNNNSVGQAVDPPS LMATSDPPQSLDTSLFFGTAATGFQQSSLNMDEVSSVSV GPLGSLDSLAMKNSSPEPQALTPSSKLTVDTDALTPSST LCENSVSELLTPTKAEWNVHPDSDFFGQEGETQFGFPNA AGNHGSQKETDLITVTGSSFLV

Database cross reference

RefSeq Protein accession:NP_009088
RefSeq Protein gi:28376656

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005634;C:nucleus;NAS:UniProtKB.

GO-F

GO:0003676;F:nucleic acid binding;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr49439

PHOSPHORYLATION

34

S

PhosphoSitePlus

485380

LTP

N