Protein basic information
LiverAtlas Protein ID |
HuLPr49439 |
Uniprot ID |
|
Uniprot Acc |
P98169;A8K151;Q9UBB3; |
Protein name |
Zinc finger X-linked protein ZXDB |
Comment |
FUNCTION:Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes (By similarity).||SUBUNIT:Self-associates. Interacts with ZXDC and CIITA (By similarity).||SUBCELLULAR LOCATION:Nucleus (Probable).||TISSUE SPECIFICITY:May be expressed in brain, heart, kidney, liver, lung, muscle and placenta.||SIMILARITY:Belongs to the ZXD family.||SIMILARITY:Contains 10 C2H2-type zinc fingers. |
Subcellular localization |
Nucleus(Probable). |
Gene name |
|
Protein sequence
|
MEIPKLLPARGTLQGGGGGGIPAGGGRVHRGPDSPAGQVP TRRLLLLRGPQDGGPGRRREEASTASRGPGPSLLAPRTD QPSGGGGGGGDDFFLVLLDPVGGDVETAGSGQAAGPVLR EEAEEGPGLQGGESGANPAGPTALGPRCLSAVPTPAPIS APGPAAAFAGTVTIHNQDLLLRFENGVLTLATPPPHAWE PGAAPAQQPGCLIAPQAGFPHAAHPGDCPELPPDLLLAE PAEPAPAPAPEEEAEGPAAALGPRGPLGSGPGVVLYLCP EAQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGW TFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLK AHMKGHEQENSFKCEVCEESFPTQAKLSAHQRSHFEPER PYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPG CSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMS KLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITH LGTKPFVCPVAGCCARFSARSSLYIHSKKHLQDVDTWKS RCPISSCNKLFTSKHSMKTHMVKRHKVGQDLLAQLEAAN SLTPSSELTSQRQNDLSDAEIVSLFSDVPDSTSAALLDT ALVNSGILTIDVASVSSTLAGHLPANNNNSVGQAVDPPS LMATSDPPQSLDTSLFFGTAATGFQQSSLNMDEVSSVSV GPLGSLDSLAMKNSSPEPQALTPSSKLTVDTDALTPSST LCENSVSELLTPTKAEWNVHPDSDFFGQEGETQFGFPNA AGNHGSQKETDLITVTGSSFLV |
Database cross reference |
RefSeq Protein accession:NP_009088
|
Liver relevance
HLPP validation |
Yes/No |
Yes |
Project name |
French Liver;Human Liver Organelles; |
Ontology annotation
GO-C |
GO:0005634;C:nucleus;NAS:UniProtKB. |
GO-F |
GO:0003676;F:nucleic acid binding;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro. |
GO-P |
GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |
Post-translational modification
LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
HuLPr49439 |
PHOSPHORYLATION |
34 |
S |
PhosphoSitePlus |
LTP |
N |