Protein basic information
| LiverAtlas Protein ID |
HuLPr49964 |
|
Uniprot ID |
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Uniprot Acc |
Q8NEJ9;A8K760;Q9Y400; |
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Protein name |
Neuroguidin |
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Comment |
FUNCTION: Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs (By similarity).||SUBUNIT: Interacts with CPEB1 and EIF4E (By similarity).||SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, axon (By similarity). Cell projection, dendrite (By similarity). Cell projection, filopodium (By similarity). Note=Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity).||ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8NEJ9-1; Sequence=Displayed; Name=2; IsoId=Q8NEJ9-2; Sequence=VSP 009935, VSP 009936; Note=May be due to a competing donor splice site;||SIMILARITY: Belongs to the SAS10 family. |
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Subcellular localization |
Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, axon (By similarity). Cell projection, dendrite (By similarity). Cell projection, filopodium (By similarity). Note=Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). |
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Gene name |
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Protein sequence
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MAALGVLESDLPSAVTLLKNLQEQVMAVTAQVKSLTQKVQ AGAYPTEKGLSFLEVKDQLLLMYLMDLTHLILDKASGGS LQGHDAVLRLVEIRTVLEKLRPLDQKLKYQIDKLIKTAV TGSLSENDPLRFKPHPSNMMSKLSSEDEEEDEAEDDQSE ASGKKSVKGVSKKYVPPRLVPVHYDETEAEREKKRLERA KRRALSSSVIRELKEQYSDAPEEIRDARHPHVTRQSQED QHRINYEESMMVRLSVSKREKGRRKRANVMSSQLHSLTH FSDISALTGGTVHLDEDQNPIKKRKKIPQKGRKKKGFRRRR |
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Database cross reference |
RefSeq Protein accession:NP_001036100
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Ontology annotation
| GO-C |
GO:0030424; C:axon; IEA:UniProtKB-SubCell. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0030425; C:dendrite; IEA:UniProtKB-SubCell. GO:0030175; C:filopodium; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. |
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GO-P |
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr49964 |
PHOSPHORYLATION |
214 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
213 |
Y |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
139 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
143 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
142 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
204 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
76 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
79 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
142 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
143 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
202 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
204 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr49964 |
PHOSPHORYLATION |
214 |
S |
PhosphoSitePlus |
LTP |
N |
|
