HuLPr49965

Uniprot ID

NGRN_HUMAN

Uniprot Acc

Q9NPE2;B2R6M8;Q4V9L7;Q9HBL4;

Protein name

Neugrin

Comment

FUNCTION: May be involved in neuronal differentiation.||SUBCELLULAR LOCATION: Nucleus. Secreted (Potential).||ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9NPE2-2; Sequence=Displayed; Name=2; IsoId=Q9NPE2-3; Sequence=VSP 039710, VSP 039711; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay;||TISSUE SPECIFICITY: Expressed at high levels in heart, brain and skeletal muscle. In brain, mainly expressed in neurons rather than glial cells.||INDUCTION: Highly up-regulated in neuroblastostoma cells by retinoic acid treatment inducing neurite outgrowth.||SIMILARITY: Belongs to the neugrin family.||SEQUENCE CAUTION: Sequence=AAF65447.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=AAG09725.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=AAG09725.1; Type=Frameshift; Positions=47; Sequence=AAH01682.1; Type=Erroneous translation; Note=Wrong choic

Subcellular localization

Nucleus. Secreted (Potential).

Gene name

neugrin, neurite outgrowth associated

Protein sequence

MAVTLSLLLGGRVCAAVTRCGFATRGVAGPGPIGREPDPD SDWEPEERELQEVESTLKRQKQAIRFQKIRRQMEAPGAP PRTLTWEAMEQIRYLHEEFPESWSVPRLAEGFDVSTDVI RRVLKSKFLPTLEQKLKQDQKVLKKAGLAHSLQHLRGSG NTSKLLPAGHSVSGSLLMPGHEASSKDPNHSTALKVIES DTHRTNTPRRRKGRNKEIQDLEESFVPVAAPLGHPRELQ KYSSDSESPRGTGSGALPSGQKLEELKAEEPDNFSSKVV QRGREFFDSNGNFLYRI

Database cross reference

RefSeq Protein accession:NP_001028260
RefSeq Protein gi:75677385

GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; NAS:UniProtKB.

GO-P

GO:0030182; P:neuron differentiation; NAS:UniProtKB.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr49965

PHOSPHORYLATION

41

S

PhosphoSitePlus

2820408

LTP

N