HuLPr49972

Uniprot ID

OVOS2_HUMAN

Uniprot Acc

Q6IE36;

Protein name

Ovostatin homolog 2

Comment

FUNCTION: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism (By similarity).||SUBUNIT: Homotetramer (By similarity).||SUBCELLULAR LOCATION: Secreted (By similarity).||SIMILARITY: Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family.||SEQUENCE CAUTION: Sequence=CAE51409.1; Type=Erroneous gene model prediction;

Subcellular localization

Secreted (By similarity).

Gene name

ovostatin 2

Protein sequence

MTGSHLSHDSWQYVLLIPSVLQEGSLDKACAQLFNLTESV VLTVSLNYGEVQTKIFEENVTGENFFKCISFEVPQARSD PLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPT YKPGQKDVNGIAQFFLDTYTFTYPNITLKDPQNNRIFQW QNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSRKTVTH QFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTF GQPVQGKTQIRVCREYFSSSNCEKNDNEICEQFIAQLEN GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEFGTGNYCM QISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFS DPNNVPMVNKLLQLELNDEFIGNYTTDENGEAQFSIDTS DIFDPEFNLKATYVRPKSCYLPSWLTPQYLDAHFLVSRF YSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDD SNVKFFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPL SISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHK VNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLL LKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDPC IPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNL HYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIAC RGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSANL SFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFF IEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQ NYEANINTWKINGSEVIQAGGRKTNIWTIIPKKLGKVNI TVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGI EKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFT VVGDILGLAMQNLVVLQMPYGGGEQNAALLASDTYVLDY LKSTEQLTEEVQSKAFFLLSNGYQ

Database cross reference

GO:0005615; C:extracellular space; IEA:InterPro.

GO-F

GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr49972

PHOSPHORYLATION

420

Y

PhosphoSitePlus

1024804

LTP

N