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Protein basic information

LiverAtlas Protein ID

HuLPr50154

Uniprot ID

TSPY3_HUMAN

Uniprot Acc

P0CV98;

Protein name

Testis-specific Y-encoded protein 3

Comment

FUNCTION: Unknown. May be involved in sperm differentiation and proliferation (By similarity).||SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity).||POLYMORPHISM: Maps to a tandemly repeated region on chromosome Yp11; additionally at least one copy is reported originating from Yq. The gene is thought to be present with an inter-individual variation in copy number and between 20 and 60 copies per Y chromosome are expected. 35 tandemly repeated gene copies on Yp11 originating from one individual have been reported (PubMed:12815422).||SIMILARITY: Belongs to the nucleosome assembly protein (NAP) family.

Subcellular localization

Cytoplasm (By similarity). Nucleus (By similarity).

Gene name

testis specific protein, Y-linked 3

Protein sequence

MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAF RMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAE EEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVE LEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPG FWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPV HLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPI EWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAE ILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS

Database cross reference

RefSeq Protein accession:NP_001071165
RefSeq Protein gi:303228330

Ontology annotation

GO-C

GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.

GO-P

GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW. GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.