Protein basic information
| LiverAtlas Protein ID |
HuLPr50250 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q8N539;A3KFK0;Q6UXK6;Q96SJ7; |
|
Protein name |
Fibrinogen C domain-containing protein 1 |
|
Comment |
FUNCTION: Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components.||SUBUNIT: Homotetramer; disulfide-linked.||SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein (Potential).||ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8N539-1; Sequence=Displayed; Name=2; IsoId=Q8N539-2; Sequence=VSP 026618, VSP 026619, VSP 026620;||TISSUE SPECIFICITY: Expressed in the small and large intestinal epithelial cells with a highly polarized localization to the apical surface corresponding to the brush border and in the ducts of the salivary gland.||SIMILARITY: Contains 1 fibrinogen C-terminal domain. |
|
Subcellular localization |
Membrane; Single-pass type II membrane protein (Potential). |
|
Gene name |
|
|
Protein sequence
|
MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALA VLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSAL VTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQA LTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTE CMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHL VNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGC ATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCD MRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEH WLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGV GLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKD RDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHAS YADGVEWSSWTGWQYSLKFSEMKIRPVREDR |
|
Database cross reference |
RefSeq Protein accession:NP_001138578
|
Ontology annotation
| GO-C |
GO:0005615; C:extracellular space; IEA:InterPro. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. |
|
GO-F |
GO:0008061; F:chitin binding; IDA:UniProtKB. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0005102; F:receptor binding; IEA:InterPro. |
|
GO-P |
GO:0007165; P:signal transduction; IEA:InterPro. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr50250 |
PHOSPHORYLATION |
265 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr50250 |
PHOSPHORYLATION |
272 |
Y |
PhosphoSitePlus |
LTP |
N |
|
